Every clinical trial should be planned this plan should include the objective of trial primary and secondary end point method of collecting data sample . Sample size for clinical trials martin bland prof of health statistics university of york outcome variables for trials how large a sample should i take. Background in this article we discuss the purpose of sample size calculation in clinical trials the need for it and the methods by which it is . Definitions sample size the number of patients or experimental units required for the trial power the probability that a clinical trial will have a significant . Drawing on various real world applications sample sizes for clinical trials takes readers through the process of calculating sample sizes for many types of clinical
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